SCHEMBL746197

SCHEMBL746197

C#CCN1CC(=O)N2[C@@H](CCC)C(=O)N(CC)C[C@@H]2N1C(=O)NCc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 19/20 0.44
CLPP Q16740 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL749070 0.95 CYP3A4 (0.43) CYP3A4CLPP
SCHEMBL749181 0.95 CYP3A4 (0.45) CYP3A4CLPP
SCHEMBL748294 0.93 CYP3A4 (0.43) CYP3A4
SCHEMBL746307 0.93 CYP3A4 (0.43) CYP3A4
SCHEMBL746560 0.93 CLPP (0.42) CYP3A4CLPP
SCHEMBL749061 0.92 CYP3A4 (0.50) CYP3A4CLPP
SCHEMBL746675 0.92 CYP3A4 (0.45) CYP3A4
SCHEMBL746620 0.92 CYP3A4 (0.42) CYP3A4
SCHEMBL746835 0.92 CYP3A4 (0.40) CYP3A4CLPP
SCHEMBL747377 0.92 CYP3A4 (0.45) CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8138337-B2 Reverse-turn mimetics and method relating thereto CHOONGWAE PHARMA CORPORATION (KR) 2012-03-20 US disclosed