Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | FUBP1 | Q96AE4 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471091 | 0.74 | ADORA2A (0.41) | GAAALDH1A1KDM4EHDAC6L3MBTL1 | |
| SCHEMBL7465821 | 0.71 | GAA (0.35) | GAA | |
| SCHEMBL577916 | 0.69 | GAA (0.39) | GAAALDH1A1HIF1APTGESKDM4E | |
| SCHEMBL8143320 | 0.69 | LMNA (0.61) | GAAALDH1A1SMN1; SMN2ESR1KDM4E | |
| SCHEMBL23704951 | 0.69 | SMN1; SMN2 (0.37) | GAAALDH1A1SMN1; SMN2HIF1AHSP90AA1 | |
| SCHEMBL29868118 | 0.69 | SMN1; SMN2 (0.37) | GAAALDH1A1SMN1; SMN2HIF1AHSP90AA1 | |
| SCHEMBL8344305 | 0.68 | RECQL (0.39) | ALDH1A1SMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL13019373 | 0.67 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2HSP90AA1HSP90AB1L3MBTL1 | |
| SCHEMBL5212887 | 0.67 | MAPT (0.42) | GAAALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7468556 | 0.66 | GAA (0.40) | GAAALDH1A1HIF1AKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819690-B1 | Herbicidal 6-thienyl and 4-thienyl pyrimidines | BASF AG (DE) | 2002-10-09 | — | — | EP | disclosed |
| US-5922726-A | Herbicidal 6-thienyl pyridines and 4-thienyl pyrimidines | AMERICAN CYANAMID COMPANY (US) | 1999-07-13 | — | — | US | disclosed |
| US-5747423-A | HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1998-05-05 | — | — | US | disclosed |
| EP-0819690-A2 | Herbicidal 6-thienyl and 4-thienyl pyrimidines | American Cyanamid Company (US) | 1998-01-21 | — | — | EP | disclosed |