Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463803 | 0.89 | ADORA2A (0.41) | ADORA2AADORA1KMT2ARAB9ANPC1 | |
| SCHEMBL7468786 | 0.88 | KMT2A (0.44) | ADORA2AADORA1KMT2ARAB9ANPC1 | |
| SCHEMBL8651967 | 0.84 | ADORA2A (0.41) | ADORA2AADORA1KMT2ARAB9ANPC1 | |
| SCHEMBL8654506 | 0.82 | ADORA2A (0.43) | ADORA2AADORA1KMT2ARAB9ANPC1 | |
| SCHEMBL7467157 | 0.77 | KMT2A (0.46) | ADORA2AADORA1KMT2ARAB9ANPC1 | |
| SCHEMBL8123680 | 0.76 | ADORA2A (0.43) | ADORA2AADORA1KMT2ARAB9ANPC1 | |
| SCHEMBL7468799 | 0.74 | ALDH1A1 (0.44) | ADORA2AADORA1KMT2ARAB9ANPC1 | |
| SCHEMBL7462001 | 0.74 | GAA (0.39) | GAAHDAC6ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL5547806 | 0.73 | KMT2A (0.50) | ADORA2AADORA1KMT2AGAAALDH1A1 | |
| SCHEMBL8123677 | 0.72 | ADORA2A (0.44) | ADORA2AADORA1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819690-B1 | Herbicidal 6-thienyl and 4-thienyl pyrimidines | BASF AG (DE) | 2002-10-09 | — | — | EP | claimed |
| US-5922726-A | Herbicidal 6-thienyl pyridines and 4-thienyl pyrimidines | AMERICAN CYANAMID COMPANY (US) | 1999-07-13 | — | — | US | claimed |
| EP-0819690-A2 | Herbicidal 6-thienyl and 4-thienyl pyrimidines | American Cyanamid Company (US) | 1998-01-21 | — | — | EP | claimed |