Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8392522 | 0.78 | EPHX1 (0.43) | EPHX1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8395750 | 0.78 | EPHX1 (0.43) | EPHX1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8391169 | 0.75 | EPHX1 (0.39) | EPHX1ALDH1A1DPP4NPC1RAB9A | |
| SCHEMBL10660120 | 0.74 | EPHX1 (0.61) | EPHX1ALDH1A1DPP4NPC1RAB9A | |
| SCHEMBL66996 | 0.74 | EPHX1 (0.61) | EPHX1ALDH1A1DPP4NPC1RAB9A | |
| SCHEMBL431289 | 0.74 | EPHX1 (0.48) | EPHX1ALDH1A1DPP4NPC1RAB9A | |
| SCHEMBL15668891 | 0.74 | EPHX1 (0.48) | EPHX1ALDH1A1DPP4NPC1RAB9A | |
| SCHEMBL14456397 | 0.74 | EPHX1 (0.48) | EPHX1ALDH1A1DPP4NPC1RAB9A | |
| SCHEMBL17316191 | 0.74 | EPHX1 (0.61) | EPHX1ALDH1A1DPP4NPC1RAB9A | |
| SCHEMBL7120046 | 0.74 | EPHX1 (0.48) | EPHX1ALDH1A1DPP4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923562-B1 | SUBSTITUTED P-TRIFLUOROMETHYLPHENYLURACILS | BAYER AG (DE) | 2002-10-09 | — | — | EP | disclosed |
| US-6444616-B1 | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-03 | — | — | US | disclosed |
| US-6130225-A | Substituted p-trifluoromethylphenyluracils | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-10 | — | — | US | disclosed |
| EP-0923562-A1 | SUBSTITUTED P-TRIFLUOROMETHYLPHENYLURACILS | BAYER AG (DE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998006706-A1 | SUBSTITUTED P-TRIFLUOROMETHYLPHENYLURACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-02-19 | — | — | WO | disclosed |