Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7461878 | 0.88 | AKR1B1 (0.35) | POLBGAACMA1ALDH1A1 | |
| SCHEMBL7463177 | 0.87 | — | — | |
| SCHEMBL7458167 | 0.86 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL8096452 | 0.85 | ALDH1A1 (0.31) | POLBGAAALDH1A1 | |
| SCHEMBL6771342 | 0.84 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL7461211 | 0.84 | ALDH1A1 (0.36) | POLBGAACMA1ALDH1A1 | |
| SCHEMBL7462956 | 0.84 | CMA1 (0.31) | POLBGAACMA1ALDH1A1 | |
| SCHEMBL7461484 | 0.84 | MEN1 (0.31) | — | |
| SCHEMBL7457439 | 0.83 | CMA1 (0.31) | CMA1ALDH1A1 | |
| SCHEMBL7460879 | 0.83 | PKM (0.34) | POLBGAACMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0908457-B1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | BASF AG (DE) | 2002-11-13 | — | — | EP | disclosed |
| US-6156700-A | 3-(1,2-Benzisothiazol- and isoxazol-5-yl)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-yl)-4(3H)-pyrimidinone or thione herbicidal agents | AMERICAN CYANMID COMPANY (US) | 2000-12-05 | — | — | US | disclosed |
| EP-0908457-A1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | American Cyanamid Company (US) | 1999-04-14 | — | — | EP | disclosed |