Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 3/20 | 0.35 |
| ▸ | BACE1 | P56817 | 3/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PMM2 | O15305 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460973 | 0.81 | MGLL (0.40) | KMT2AMEN1POLBCHRM3ALDH1A1 | |
| SCHEMBL7462955 | 0.81 | MEN1 (0.56) | HDAC1HDAC6KMT2AMEN1POLB | |
| SCHEMBL3115953 | 0.77 | ALDH1A1 (0.51) | KMT2AL3MBTL1MEN1POLBGSK3B | |
| SCHEMBL7463278 | 0.72 | GSK3A (0.61) | HDAC1HDAC6KMT2AMEN1POLB | |
| SCHEMBL7469357 | 0.72 | KCNN4 (0.47) | GRIN2B | |
| SCHEMBL3846036 | 0.68 | ALDH1A1 (0.62) | KMT2AL3MBTL1MEN1CHRM3ALDH1A1 | |
| SCHEMBL28763499 | 0.67 | ALDH1A1 (0.42) | HDAC1HDAC6KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL7051934 | 0.66 | ALDH1A1 (0.48) | HDAC1HDAC6KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL7050527 | 0.66 | HDAC1 (0.49) | HDAC1HDAC6KMT2AL3MBTL1MEN1 | |
| SCHEMBL11861528 | 0.66 | HDAC1 (0.60) | HDAC1HDAC6KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214305-A1 | BENZYLIDENE-THIAZOLIDINEDIONES AND ANALOGUES AND THEIR USE IN THE TREATMENT OF INFLAMMATION | Maxia Pharmaceuticals, Inc. (US) | 2002-06-19 | — | — | EP | claimed |
| WO-2001016123-A1 | BENZYLIDENE-THIAZOLIDINEDIONES AND ANALOGUES AND THEIR USE IN THE TREATMENT OF INFLAMMATION | MAXIA PHARMACEUTICALS, INC. (US) | 2001-03-08 | — | — | WO | claimed |