Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | INSR | P06213 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463297 | 1.00 | SNCA (0.38) | SNCAMAPTRAB9AMEN1KMT2A | |
| SCHEMBL7472221 | 0.83 | CYP2A6 (0.43) | SNCAMAPTRAB9AMEN1KMT2A | |
| SCHEMBL7465197 | 0.81 | MAPT (0.54) | SNCAMAPTRAB9AMEN1KMT2A | |
| SCHEMBL31074949 | 0.81 | MAPT (0.54) | SNCAMAPTRAB9AMEN1KMT2A | |
| SCHEMBL7465202 | 0.81 | MAPT (0.54) | SNCAMAPTRAB9AMEN1KMT2A | |
| SCHEMBL16151071 | 0.79 | MAPT (0.57) | SNCAMAPTRAB9AMEN1KMT2A | |
| SCHEMBL16151070 | 0.75 | CYP3A4 (0.60) | MAPTRAB9AMEN1KMT2AALOX5 | |
| SCHEMBL16151072 | 0.75 | CYP3A4 (0.60) | MAPTRAB9AMEN1KMT2AALOX5 | |
| SCHEMBL16155795 | 0.71 | ATP4A (0.56) | KMT2AALDH1A1LMNACYP3A4ATP4A | |
| SCHEMBL3139327 | 0.66 | PI4KA (0.58) | MAPTRAB9AKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771796-B1 | Substituted S-triazines and process for their preparation | AGFA GEVAERT (BE) | 2002-06-19 | — | — | EP | disclosed |
| EP-0771796-A1 | Substituted S-triazines and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-07 | — | — | EP | disclosed |