Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 18/20 | 0.42 |
| ▸ | FNTB | P49356 | 18/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 18/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468926 | 0.78 | FNTA (0.44) | FNTAFNTBPGGT1B | |
| SCHEMBL7162634 | 0.72 | FNTA (0.52) | FNTAFNTBPGGT1B | |
| SCHEMBL7743208 | 0.71 | FNTA (0.47) | FNTAFNTBPGGT1BGPR119 | |
| SCHEMBL7465336 | 0.71 | FNTA (0.47) | FNTAFNTBPGGT1B | |
| SCHEMBL7743244 | 0.69 | GPR119 (0.49) | FNTAFNTBGPR119 | |
| SCHEMBL7747674 | 0.67 | FNTA (0.45) | FNTAFNTBPGGT1BGPR119 | |
| SCHEMBL7465329 | 0.66 | FNTA (0.81) | FNTAFNTBPGGT1B | |
| SCHEMBL7747657 | 0.66 | FNTA (0.42) | FNTAFNTBPGGT1BGPR119 | |
| SCHEMBL7743228 | 0.64 | FNTA (0.43) | FNTAFNTBPGGT1BGPR119 | |
| SCHEMBL7466130 | 0.64 | FNTA (0.49) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165082-A4 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2002-06-12 | — | — | EP | disclosed |
| EP-1165082-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000051611-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2000-09-08 | — | — | WO | disclosed |