Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | RORC | P51449 | 9/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468900 | 1.00 | MAPT (0.37) | MAPTTDP1NPSR1KDM4EKMT2A | |
| SCHEMBL7464677 | 0.91 | MMP2 (0.41) | CA1CA2RORC | |
| SCHEMBL7467700 | 0.91 | MMP2 (0.41) | CA1CA2RORC | |
| SCHEMBL7470889 | 0.89 | NPSR1 (0.35) | MAPTNPSR1CA1CA2GAA | |
| SCHEMBL7475987 | 0.89 | NPSR1 (0.35) | MAPTNPSR1CA1CA2GAA | |
| Trifluoroacetic Acid SCHEMBL8742783 | 0.86 | TDP1 (0.36) | TDP1NPSR1CA1CA2GAA | |
| Trifluoroacetic Acid SCHEMBL8742823 | 0.86 | TDP1 (0.36) | TDP1NPSR1CA1CA2GAA | |
| SCHEMBL8593348 | 0.83 | NPSR1 (0.39) | MAPTNPSR1KDM4EGAA | |
| SCHEMBL8593351 | 0.83 | NPSR1 (0.39) | MAPTNPSR1KDM4EGAA | |
| SCHEMBL8589703 | 0.80 | CA1 (0.34) | MAPTTDP1NPSR1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-B1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI SYNTHELABO (FR) | 2002-02-27 | — | — | EP | disclosed |
| WO-1995018105-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-07-06 | — | — | WO | disclosed |