Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.53 |
| ▸ | XIAP | P98170 | 5/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477934 | 0.95 | ACE (0.56) | ACEXIAPF2OPRK1OPRM1 | |
| SCHEMBL9450535 | 0.95 | ACE (0.54) | ACEXIAPF2OPRK1 | |
| SCHEMBL7473007 | 0.93 | ACE (0.52) | ACEXIAPF2OPRK1OPRM1 | |
| SCHEMBL9450538 | 0.92 | ACE (0.54) | ACEXIAPF2OPRK1OPRM1 | |
| SCHEMBL7471889 | 0.91 | OPRD1 (0.53) | ACEOPRK1OPRM1 | |
| SCHEMBL9450537 | 0.90 | OPRK1 (0.54) | ACEXIAPF2OPRK1OPRM1 | |
| SCHEMBL9450517 | 0.89 | ACE (0.51) | ACEF2OPRK1OPRM1 | |
| SCHEMBL9450523 | 0.89 | ACE (0.56) | ACEXIAPF2OPRK1OPRM1 | |
| SCHEMBL9710298 | 0.87 | ACE (0.51) | ACEXIAPF2OPRK1 | |
| SCHEMBL9450571 | 0.85 | XIAP (0.48) | XIAPOPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230243-A1 | POYCYLOALKYLPURINES AS ADENOSINE RECEPTOR ANTAGONISTS | BIOGEN, INC. (US) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001034610-A1 | POLYCYCLOALKYLPURINES AS ADENOSINE RECEPTOR ANTAGONISTS | BIOGEN, INC. (US) | 2001-05-17 | — | — | WO | disclosed |