Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.74 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.66 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.64 |
| ▸ | CNR1 | P21554 | 2/20 | 0.58 |
| ▸ | CNR2 | P34972 | 2/20 | 0.58 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.57 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | AURKA | O14965 | 4/20 | 0.54 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.54 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468656 | 0.89 | HTT (0.67) | HTTNTRK1NR2F2AURKAMAPK1 | |
| SCHEMBL9921352 | 0.86 | HTT (0.81) | HTTNR2F2CNR1CNR2TTBK1 | |
| SCHEMBL7469491 | 0.82 | HTT (0.56) | HTTNTRK1NR2F2CNR1CNR2 | |
| SCHEMBL8545770 | 0.82 | HTT (0.82) | HTTNR2F2CNR1CNR2TTBK1 | |
| SCHEMBL7470174 | 0.82 | HTT (0.57) | HTTNTRK1NR2F2AURKAPIK3CD | |
| SCHEMBL9921421 | 0.79 | PIK3CD (0.70) | HTTNR2F2CNR1CNR2CYP1A2 | |
| SCHEMBL7467527 | 0.78 | PDE5A (0.64) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19160676 | 0.78 | HTT (0.85) | HTTNR2F2CNR1CNR2TTBK1 | |
| SCHEMBL18733232 | 0.78 | HTT (1.00) | HTTNR2F2CNR1CNR2TTBK1 | |
| SCHEMBL8543977 | 0.78 | HTT (0.64) | HTTNTRK1NR2F2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |