Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.67 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.59 |
| ▸ | USP10 | Q14694 | 1/20 | 0.57 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.57 |
| ▸ | USP13 | Q92995 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.52 |
| ▸ | AURKA | O14965 | 4/20 | 0.52 |
| ▸ | CCNC | P24863 | 1/20 | 0.49 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470174 | 0.92 | HTT (0.57) | HTTNTRK1USP10PIK3C3USP13 | |
| SCHEMBL7464247 | 0.89 | HTT (0.74) | HTTNTRK1MAPK1MEN1STAT3 | |
| SCHEMBL7469214 | 0.86 | USP10 (0.76) | HTTUSP10PIK3C3USP13MAPK1 | |
| SCHEMBL9921342 | 0.83 | HTT (0.73) | HTTNTRK1USP10PIK3C3USP13 | |
| SCHEMBL7461671 | 0.81 | HTT (0.52) | HTTNTRK1USP10PIK3C3USP13 | |
| SCHEMBL7467527 | 0.80 | PDE5A (0.64) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9921353 | 0.80 | HTT (0.77) | HTTUSP10PIK3C3USP13MAPK1 | |
| SCHEMBL9921352 | 0.80 | HTT (0.81) | HTTUSP10PIK3C3USP13MAPK1 | |
| SCHEMBL13191858 | 0.80 | HTT (1.00) | HTTUSP10PIK3C3USP13MAPK1 | |
| SCHEMBL7469972 | 0.80 | EGFR (0.51) | HTTNTRK1MAPK1MEN1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |