Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016228 | 0.81 | PPARG (0.50) | CALM1ALDH1A1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL7959794 | 0.80 | CALM1 (0.57) | CALM1ALDH1A1CYP3A4TAAR1 | |
| SCHEMBL19665419 | 0.79 | CALM1 (0.50) | CALM1ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL19679885 | 0.78 | AKR1B1 (0.38) | CALM1ALDH1A1TDP1SMN1; SMN2HPGD | |
| SCHEMBL19665514 | 0.77 | AKR1B1 (0.61) | HTR2CHTR2B | |
| Dihydro-5,6-Dehydrokawain SCHEMBL19679894 | 0.76 | PPARG (0.59) | ALDH1A1CYP3A4TDP1RAB9ASMN1; SMN2 | |
| SCHEMBL29928731 | 0.75 | PTPN1 (0.59) | CALM1ALDH1A1TDP1TAAR1LMNA | |
| SCHEMBL30007673 | 0.75 | CALM1 (1.00) | CALM1ALDH1A1CYP3A4RAB9ASMN1; SMN2 | |
| SCHEMBL108087 | 0.73 | TAAR1 (0.77) | CALM1ALDH1A1CYP3A4TAAR1GAA | |
| SCHEMBL31272047 | 0.72 | POLB (0.53) | ALDH1A1CYP3A4SMN1; SMN2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032572-B1 | PYRANONES, METHOD FOR THE PRODUCTION AND USE THEREOF | SCHWABE WILLMAR GMBH & CO (DE) | 2002-12-11 | — | — | EP | disclosed |
| US-6288109-B1 | Pyranones, method for the production and use thereof | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 2001-09-11 | — | — | US | disclosed |
| EP-1032572-A2 | PYRANONES, METHOD FOR THE PRODUCTION AND USE THEREOF | Dr. Willmar Schwabe GmbH & Co. (DE) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999025716-A9 | PYRANONES, METHOD FOR THE PRODUCTION AND USE THEREOF | SCHWABE WILLMAR GMBH & CO (DE) | 1999-09-02 | — | — | WO | disclosed |
| WO-1999025716-A2 | PYRANONES, METHOD FOR THE PRODUCTION AND USE THEREOF | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1999-05-27 | — | — | WO | disclosed |