Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 7/20 | 1.00 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.58 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.58 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.58 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.58 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | NOS2 | P35228 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27183336 | 0.77 | CALM1 (0.63) | CALM1LMNACYP3A4 | |
| SCHEMBL27254011 | 0.77 | CALM1 (1.00) | CALM1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL29862145 | 0.77 | CALM1 (0.86) | CALM1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL16568144 | 0.77 | CALM1 (0.86) | CALM1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL108087 | 0.76 | TAAR1 (0.77) | CALM1CYP3A4ALDH1A1 | |
| SCHEMBL1937213 | 0.75 | CALM1 (0.60) | CALM1NPC1LMNAHPGDRAB9A | |
| SCHEMBL30451939 | 0.75 | CALM1 (0.81) | CALM1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL7464294 | 0.75 | CALM1 (0.60) | CALM1NPC1LMNAHPGDRAB9A | |
| Batatasin Iii SCHEMBL29629601 | 0.74 | GABRA1 (1.00) | CALM1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL30574244 | 0.74 | GABRA1 (0.87) | CALM1GABRA1GABRG2GABRB3GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022236789-A1 | EXTRACT OF DENDROBIUM SINENSE, DENDROBIUM DENSIFLORUM, OR DENDROBIUM BENSONIAE, AND APPLICATION OF MAIN COMPONENTS THEREOF AS ANTI-INFLAMMATORY FORMULATION | 中国热带农业科学院热带生物技术研究所 | 2022-11-17 | — | — | WO | claimed |
| WO-2022236789-A1 | EXTRACT OF DENDROBIUM SINENSE, DENDROBIUM DENSIFLORUM, OR DENDROBIUM BENSONIAE, AND APPLICATION OF MAIN COMPONENTS THEREOF AS ANTI-INFLAMMATORY FORMULATION | 中国热带农业科学院热带生物技术研究所 | 2022-11-17 | — | — | WO | disclosed |
| WO-2022236789-A1 | EXTRACT OF DENDROBIUM SINENSE, DENDROBIUM DENSIFLORUM, OR DENDROBIUM BENSONIAE, AND APPLICATION OF MAIN COMPONENTS THEREOF AS ANTI-INFLAMMATORY FORMULATION | 中国热带农业科学院热带生物技术研究所 | 2022-11-17 | — | — | WO | disclosed |