Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.36 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.36 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946681 | 0.84 | NPSR1 (0.42) | MAPTALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL6946687 | 0.84 | NPSR1 (0.42) | MAPTALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL6664572 | 0.78 | HTT (0.50) | MAPTALDH1A1LMNAKMT2AHTT | |
| SCHEMBL6664578 | 0.78 | HTT (0.50) | MAPTALDH1A1LMNAKMT2AHTT | |
| SCHEMBL6942168 | 0.78 | HTT (0.50) | MAPTALDH1A1LMNAKMT2AHTT | |
| SCHEMBL4649042 | 0.76 | MMP1 (0.49) | MAPTALDH1A1NPSR1MEN1NFKB1 | |
| SCHEMBL4649040 | 0.76 | MMP1 (0.49) | MAPTALDH1A1NPSR1MEN1NFKB1 | |
| SCHEMBL4647175 | 0.73 | NPSR1 (0.40) | MAPTALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL21900269 | 0.72 | TSHR (0.39) | ALDH1A1LMNATSHR | |
| SCHEMBL19563725 | 0.72 | TSHR (0.39) | ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235826-A1 | QUINUCLIDINE ACRYLAMIDES | AstraZeneca AB (SE) | 2002-09-04 | — | — | EP | claimed |
| WO-2001029034-A1 | QUINUCLIDINE ACRYLAMIDES | ASTRAZENECA AB (SE) | 2001-04-26 | — | — | WO | claimed |