Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799395 | 0.86 | PDE4A (0.50) | ALDH1A1HPGDL3MBTL1RXFP1PDE4B | |
| SCHEMBL6799259 | 0.85 | ALDH1A1 (0.50) | ALDH1A1HPGDL3MBTL1RXFP1PDE4B | |
| SCHEMBL6803285 | 0.84 | TP53 (0.47) | ALDH1A1HPGDL3MBTL1RXFP1PDE4B | |
| SCHEMBL6796416 | 0.84 | ALDH1A1 (0.46) | ALDH1A1HPGDL3MBTL1RXFP1PDE4B | |
| SCHEMBL6796816 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HPGDL3MBTL1RXFP1PDE4B | |
| SCHEMBL6804709 | 0.79 | RXFP1 (0.48) | ALDH1A1HPGDL3MBTL1RXFP1PDE4B | |
| SCHEMBL6793249 | 0.79 | GRM5 (0.44) | ALDH1A1HPGDL3MBTL1RXFP1PDE4B | |
| SCHEMBL6797576 | 0.79 | HPGD (0.44) | ALDH1A1HPGDL3MBTL1RXFP1PDE4B | |
| SCHEMBL6797485 | 0.78 | GAA (0.43) | ALDH1A1PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6799545 | 0.77 | ALOX15 (0.58) | ALDH1A1HPGDRXFP1PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6426345-B1 | PHOSPHODIESTERASE INHIBITORS; ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-07-30 | — | — | US | disclosed |