Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.39 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.39 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 15/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 14/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19817011 | 1.00 | SLC6A1 (0.39) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| SCHEMBL25105583 | 0.96 | SLC6A2 (0.41) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| SCHEMBL1496060 | 0.91 | SLC6A2 (0.36) | SLC6A4SLC6A2SLC6A3RENCYP2D6 | |
| SCHEMBL31211305 | 0.90 | REN (0.38) | SLC6A4SLC6A2SLC6A3REN | |
| SCHEMBL25105977 | 0.86 | SLC6A2 (0.48) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL25105353 | 0.86 | SLC6A2 (0.48) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL25260214 | 0.86 | SLC6A2 (0.48) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL1958503 | 0.85 | SLC6A2 (0.39) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL15363207 | 0.82 | USP30 (0.45) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| SCHEMBL3699616 | 0.82 | USP30 (0.45) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1116295-C | Cycloalkylaminomethylpyrrolidine derivatives | DAIICHI SEIYAKU CO (JP) | 2003-07-30 | — | — | CN | disclosed |
| EP-0900793-B1 | CYCLOALKYLAMINOMETHYLPYRROLIDINE DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2002-07-24 | — | — | EP | disclosed |
| US-6194434-B1 | MICROBIOCIDES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-02-27 | — | — | US | disclosed |
| CN-1222151-A | Cycloalkylaminomethylpyrrolidine derivatives | DAIICHI SEIYAKU CO (JP) | 1999-07-07 | — | — | CN | disclosed |
| EP-0900793-A1 | CYCLOALKYLAMINOMETHYLPYRROLIDINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |