SCHEMBL7464405

SCHEMBL7464405

CC(C)(C)OC(=O)[C@H](N)Cc1ccc(O)cc1

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.57
TAAR1 Q96RJ0 3/20 0.49
SLC6A2 P23975 1/20 0.49
ESR1 P03372 3/20 0.46
ESR2 Q92731 2/20 0.46
CTSS P25774 1/20 0.46
CTSK P43235 1/20 0.46
HDAC8 Q9BY41 2/20 0.44
LY96 Q9Y6Y9 1/20 0.44
BLM P54132 1/20 0.42
ERAP2 Q6P179 1/20 0.42
LNPEP Q9UIQ6 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL630703 1.00 SLC7A5 (0.57) SLC7A5TAAR1SLC6A2ESR1ESR2
SCHEMBL594571 1.00 SLC7A5 (0.57) SLC7A5TAAR1SLC6A2ESR1ESR2
Hydrochloric Acid SCHEMBL27704336 0.98 SLC7A5 (0.56) SLC7A5TAAR1SLC6A2ESR1ESR2
Hydrochloric Acid SCHEMBL4422991 0.98 SLC7A5 (0.56) SLC7A5TAAR1SLC6A2ESR1ESR2
Hydrochloric Acid SCHEMBL7687022 0.98 SLC7A5 (0.56) SLC7A5TAAR1SLC6A2ESR1ESR2
SCHEMBL7395431 0.88 ACACB (0.44) SLC7A5ESR1ESR2CTSSCTSK
SCHEMBL6666822 0.87 SLC7A5 (0.45) SLC7A5
SCHEMBL3203564 0.87 SLC7A5 (0.45) SLC7A5
SCHEMBL17978113 0.87 SLC7A5 (0.45) SLC7A5
SCHEMBL17978114 0.87 SLC7A5 (0.45) SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20240101642-A1 SYSTEM AND METHOD FOR HOMOGENOUS GPCR PHOSPHORYLATION AND IDENTIFICATION OF BETA-2 ADRENERGIC RECEPTOR POSITIVE ALLOSTERIC MODULATORS DUKE UNIVERSITY 2024-03-28 US disclosed
US-11879038-B2 Supramolecular gel supported on open-cell polymer foam UNIVERSITE DE STRASBOURG (FR) 2024-01-23 US disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
US-11866482-B2 System and method for homogenous GPCR phosphorylation and identification of beta-2 adrenergic receptor positive allosteric modulators DUKE UNIVERSITY (US) 2024-01-09 US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220315710-A1 SUPRAMOLECULAR GEL SUPPORTED ON OPEN-CELL POLYMER FOAM INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2022-10-06 US disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
CN-100528842-C Diphenylazetidinone derivatives for the treatment of disorders of lipid metabolism ASTRAZENECA AB (SE) 2009-08-19 CN disclosed
CN-101058556-A Diphenylacetidinon derivatives for treatment of disordered lipid metabolism, method of production thereof(variants), pharmaceutical composition ASTRAZENECA AB (SE) 2007-10-24 CN disclosed
CN-1665783-A Diphenylazetidinone derivatives for the treatment of disorders of lipid metabolism ASTRAZENECA AB (SE) 2005-09-07 CN disclosed
CN-1204889-C Adhesion receptor antagonists MERCK PATENT GMBH (DE) 2005-06-08 CN disclosed
EP-0697408-B1 1 substituted-phenyl-oxazolidene-2-one derivatives and their use as adhesion-receptor antagonists MERCK PATENT GMBH (DE) 2002-01-23 EP disclosed
CN-1125575-A Adhesion receptor antagonists MERCK PATENT GMBH (DE) 1996-07-03 CN disclosed
EP-0697408-A1 1 substituted-phenyl-oxazolidene-2-one derivatives and their use as adhesion-receptor antagonists MERCK PATENT GmbH (DE) 1996-02-21 EP disclosed
US-4572894-A USING AMINOACYL-TRNA SYNTHETASE AS CONDENSING AGENT Imahori, Kazutomo (JP) 1986-02-25 US disclosed
EP-0086053-B1 PROCESS FOR SYNTHESIZING PEPTIDES OR PEPTIDE DERIVATIVES Imahori, Kazutomo (JP) 1986-01-02 EP disclosed
EP-0086053-A1 Process for synthesizing peptides or peptide derivatives Imahori, Kazutomo (JP) 1983-08-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240101642-A1 SYSTEM AND METHOD FOR HOMOGENOUS GPCR PHOSPHORYLATION AND IDENTIFICATION OF BETA-2 ADRENERGIC RECEPTOR POSITIVE ALLOSTERIC MODULATORS ADRB2, ARRB1, ADRB1 SLC7A5 4655/4885TAAR1 568/4885SLC6A2 1616/4885
US-11866482-B2 System and method for homogenous GPCR phosphorylation and identification of beta-2 adrenergic receptor positive allosteric modulators ADRB2, ARRB1, ADRB1 SLC7A5 4655/4885TAAR1 568/4885SLC6A2 1616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.