Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.33 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PLK4 | O00444 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.33 |
| ▸ | INSR | P06213 | 2/20 | 0.33 |
| ▸ | LCK | P06239 | 2/20 | 0.33 |
| ▸ | FYN | P06241 | 2/20 | 0.33 |
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
| ▸ | LYN | P07948 | 2/20 | 0.33 |
| ▸ | MET | P08581 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467328 | 0.92 | ALDH1A1 (0.39) | HDAC2HDAC1CSNK2A1CLK4KDR | |
| SCHEMBL7454356 | 0.84 | HDAC2 (0.33) | HDAC2HDAC1CSNK2A1CLK4KDR | |
| SCHEMBL7460024 | 0.82 | CYP1A2 (0.45) | HDAC2HDAC1CSNK2A1CLK4ALDH1A1 | |
| SCHEMBL7461827 | 0.81 | HDAC2 (0.34) | HDAC2HDAC1CSNK2A1 | |
| SCHEMBL6572728 | 0.80 | FCGR3B (0.38) | HDAC2HDAC1ALDH1A1ABL1CYP3A4 | |
| SCHEMBL6572585 | 0.80 | ALDH1A1 (0.42) | CLK4ALDH1A1MAP4K4MINK1SRPK1 | |
| SCHEMBL7458534 | 0.80 | HDAC2 (0.39) | HDAC2HDAC1CSNK2A1CLK4ALDH1A1 | |
| SCHEMBL6572942 | 0.79 | APP (0.41) | ALDH1A1ABL1CYP3A4HSD17B10MEN1 | |
| SCHEMBL6571323 | 0.79 | ALDH1A1 (0.35) | KDRALDH1A1ABL1AURKBJAK2 | |
| SCHEMBL6572249 | 0.78 | MAPT (0.44) | KDRALDH1A1KITCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0963982-B1 | New diaminobenzene derivatives and these componends containing colouring agents | WELLA AG (DE) | 2002-03-13 | — | — | EP | disclosed |
| US-6132475-A | FOR OXIDATION DYEING OF KERATIN FIBERS; INCLUDES COUPLER AND DEVELOPER, IN WHICH THE DEVELOPER IS A SUBSTITUTED 2-(FURYL, THIENYL, PYRROLYL, OR SELENOPHENE) P-DIAMINOBENZENE DERIVATIVE OF GIVEN FORMULA; COLORFASTNESS, WASHFASTNESS | WELLA AKTIENGESELLSCHAFT (DE) | 2000-10-17 | — | — | US | disclosed |
| EP-0963982-A2 | New diaminobenzene derivatives and these componends containing colouring agents | Wella Aktiengesellschaft (DE) | 1999-12-15 | — | — | EP | disclosed |