SCHEMBL7464449

SCHEMBL7464449

Cc1ccccc1NCc1cscc1-c1cc(N)ccc1N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.42
ALDH1A1 P00352 3/20 0.42
HTT P42858 3/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
ADRA2C P18825 3/20 0.37
GAA P10253 2/20 0.35
TP53 P04637 1/20 0.35
MAPK1 P28482 1/20 0.35
HSD17B10 Q99714 1/20 0.35
GRIN2D O15399 2/20 0.34
GRIN3B O60391 2/20 0.34
GRIN1 Q05586 2/20 0.34
GRIN2A Q12879 2/20 0.34
GRIN2B Q13224 2/20 0.34
GRIN2C Q14957 2/20 0.34
GRIN3A Q8TCU5 2/20 0.34
SIGMAR1 Q99720 2/20 0.34
KDM4E B2RXH2 2/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7465392 0.99 MAPT (0.44) MAPTALDH1A1HTTKMT2AMEN1
SCHEMBL7463054 0.89 MAPT (0.33) MAPTALDH1A1HTTKMT2AMEN1
Hydrochloric Acid SCHEMBL8076382 0.88 MAPT (0.33) MAPTALDH1A1HTTKMT2AMEN1
SCHEMBL7460493 0.82 ADRA2B (0.37) MAPTALDH1A1HTTKMT2AMEN1
Hydrochloric Acid SCHEMBL7455787 0.81 ADRA2B (0.36) MAPTALDH1A1HTTKMT2AMEN1
SCHEMBL7461663 0.81 MAPT (0.37) MAPTALDH1A1KMT2AMEN1POLB
SCHEMBL7459664 0.80 MAPT (0.43) MAPTALDH1A1HTTKMT2AMEN1
SCHEMBL6272131 0.80 MAPT (0.51) MAPTALDH1A1HTTKMT2AMEN1
Hydrochloric Acid SCHEMBL7455759 0.80 MAPT (0.36) MAPTALDH1A1KMT2AMEN1POLB
Hydrochloric Acid SCHEMBL7456853 0.79 MAPT (0.42) MAPTALDH1A1HTTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0963982-B1 New diaminobenzene derivatives and these componends containing colouring agents WELLA AG (DE) 2002-03-13 EP claimed
US-6132475-A FOR OXIDATION DYEING OF KERATIN FIBERS; INCLUDES COUPLER AND DEVELOPER, IN WHICH THE DEVELOPER IS A SUBSTITUTED 2-(FURYL, THIENYL, PYRROLYL, OR SELENOPHENE) P-DIAMINOBENZENE DERIVATIVE OF GIVEN FORMULA; COLORFASTNESS, WASHFASTNESS WELLA AKTIENGESELLSCHAFT (DE) 2000-10-17 US claimed
EP-0963982-A2 New diaminobenzene derivatives and these componends containing colouring agents Wella Aktiengesellschaft (DE) 1999-12-15 EP claimed
EP-0963982-B1 New diaminobenzene derivatives and these componends containing colouring agents WELLA AG (DE) 2002-03-13 EP disclosed
US-6132475-A FOR OXIDATION DYEING OF KERATIN FIBERS; INCLUDES COUPLER AND DEVELOPER, IN WHICH THE DEVELOPER IS A SUBSTITUTED 2-(FURYL, THIENYL, PYRROLYL, OR SELENOPHENE) P-DIAMINOBENZENE DERIVATIVE OF GIVEN FORMULA; COLORFASTNESS, WASHFASTNESS WELLA AKTIENGESELLSCHAFT (DE) 2000-10-17 US disclosed
EP-0963982-A2 New diaminobenzene derivatives and these componends containing colouring agents Wella Aktiengesellschaft (DE) 1999-12-15 EP disclosed