Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 6/20 | 0.86 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.86 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.86 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.86 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.86 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | BRD4 | O60885 | 4/20 | 0.71 |
| ▸ | BRD2 | P25440 | 2/20 | 0.71 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.71 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.71 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PDE1A | P54750 | 1/20 | 0.49 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3902928 | 0.93 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7031729 | 0.92 | MEN1 (0.87) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL516463 | 0.89 | PDE4A (0.81) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL21381257 | 0.88 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL9565477 | 0.86 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL11462282 | 0.85 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL1495090 | 0.85 | PDE4A (0.76) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7457891 | 0.84 | MEN1 (1.00) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL27600173 | 0.84 | BRD4 (0.70) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7763730 | 0.83 | ADORA2A (0.82) | PDE4APDE4BPDE4CPDE4DADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0960884-B1 | Process for the production of 3,7-dialkylxanthins from 3-alkylxanthins | AVENTIS PHARMA GMBH (DE) | 2002-10-09 | — | — | EP | claimed |
| EP-0597377-B1 | Process for the production of 3,7-Dialkylxanthine from 3-Alkylxanthine | AVENTIS PHARMA GMBH (DE) | 2000-08-16 | — | — | EP | claimed |
| EP-0960884-A1 | Process for the production of 3,7-dialkylxanthins from 3-alkylxanthins | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-12-01 | — | — | EP | claimed |
| US-5475107-A | Process for obtaining 3,7-dialkylxanthines from 3-alkyl-xanthines | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1995-12-12 | — | — | US | claimed |
| EP-0597377-A1 | Process for the production of 3,7-Dialkylxanthine from 3-Alkylxanthine | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-18 | — | — | EP | claimed |
| EP-0960884-B1 | Process for the production of 3,7-dialkylxanthins from 3-alkylxanthins | AVENTIS PHARMA GMBH (DE) | 2002-10-09 | — | — | EP | disclosed |
| EP-0771813-B1 | Alkylxanthine phosphonates and alkylxanthine phosphine oxydes and their use as medicines | HOECHST AG (DE) | 2002-01-16 | — | — | EP | disclosed |
| EP-0597377-B1 | Process for the production of 3,7-Dialkylxanthine from 3-Alkylxanthine | AVENTIS PHARMA GMBH (DE) | 2000-08-16 | — | — | EP | disclosed |
| EP-0960884-A1 | Process for the production of 3,7-dialkylxanthins from 3-alkylxanthins | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-12-01 | — | — | EP | disclosed |
| US-5922868-A | 1-(4,4-ETHYLENEDIOXY-3-METHYLPENTYL)-3-METHYL-7-PROPYLXANTHINE | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-07-13 | — | — | US | disclosed |
| US-5728686-A | TREATMENT OF MUSCULAR DYSTROPHY | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-17 | — | — | US | disclosed |
| EP-0771813-A1 | Alkylxanthine phosphonates and alkylxanthine phosphine oxydes and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-07 | — | — | EP | disclosed |
| EP-0413278-B1 | Use of xanthine derivatives against peptic ulcers | HOECHST JAPAN (JP) | 1996-11-06 | — | — | EP | disclosed |
| US-5475107-A | Process for obtaining 3,7-dialkylxanthines from 3-alkyl-xanthines | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1995-12-12 | — | — | US | disclosed |
| EP-0597377-A1 | Process for the production of 3,7-Dialkylxanthine from 3-Alkylxanthine | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-18 | — | — | EP | disclosed |
| EP-0570831-A2 | Use of Xanthinderivatives for treatment of cerebral nerve dammages after disruption of the blood circulation | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-24 | — | — | EP | disclosed |
| US-5109003-A | METHOD FOR THE TREATMENT OF PEPTIC ULCER DISEASE | HOECHST JAPAN LIMITED (JP) | 1992-04-28 | — | — | US | disclosed |