Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 18/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 18/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 18/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464580 | 1.00 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL7467813 | 0.83 | CHRNB2 (0.38) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL7457630 | 0.82 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL7463371 | 0.82 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL7464221 | 0.81 | SLC6A2 (0.32) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL7460391 | 0.81 | SLC6A2 (0.32) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL7470546 | 0.81 | SLC6A2 (0.32) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL7458106 | 0.81 | SLC6A2 (0.32) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL7466435 | 0.80 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL7464583 | 0.79 | CHRNA3 (0.37) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212319-A2 | 3-PYRROLIDINYLOXY-3'-PYRIDYL ETHER COMPOUNDS USEFUL FOR CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001019817-A2 | 3-PYRROLIDINYLOXY-3'-PYRIDYL ETHER COMPOUNDS USEFUL FOR CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 2001-03-22 | — | — | WO | disclosed |