Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7611700 | 0.79 | EPHX1 (0.61) | EPHX1NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL966980 | 0.76 | EPHX1 (0.56) | EPHX1NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL3771418 | 0.76 | EPHX1 (0.34) | EPHX1NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL28529404 | 0.74 | EPHX1 (0.54) | EPHX1NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL8305980 | 0.73 | EPHX1 (0.52) | EPHX1NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL10442649 | 0.73 | EPHX1 (0.31) | EPHX1NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL967797 | 0.73 | EPHX1 (0.52) | EPHX1NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL14794983 | 0.73 | EPHX1 (0.52) | EPHX1NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL7314345 | 0.71 | EPHX1 (0.47) | EPHX1RAB9AKDM4EALDH1A1CYP3A4 | |
| SCHEMBL966654 | 0.71 | EPHX1 (0.50) | EPHX1NPC1SMN1; SMN2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025692-B1 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1982-12-01 | — | — | EP | claimed |
| EP-0025692-A1 | Quinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-03-25 | — | — | EP | claimed |
| CN-109476841-B | Novel polymer derivative and novel polymer derivative imaging probe using same | 日本化药株式会社 | 2021-08-24 | — | — | CN | disclosed |
| CN-107249589-B | Physiologically active substance-binding block copolymer | 日本化药株式会社 | 2021-06-08 | — | — | CN | disclosed |
| US-10973762-B2 | Active-targeting-type polymer derivative, composition containing said polymer derivative, and uses of said polymer derivative and said composition | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2021-04-13 | — | — | US | disclosed |
| US-10869937-B2 | Polymer derivatives, and novel polymer derivative imaging probe using same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2020-12-22 | — | — | US | disclosed |
| EP-3263107-B1 | BLOCK COPOLYMER CONJUGATE OF PHYSIOLOGICALLY ACTIVE SUBSTANCE | NIPPON KAYAKU KK (JP) | 2020-11-11 | — | — | EP | disclosed |
| US-10814016-B2 | — | — | 2020-10-27 | — | — | US | disclosed |
| US-20190307905-A1 | Novel Polymer Derivatives, And Novel Polymer Derivative Imaging Probe Using Same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2019-10-10 | — | — | US | disclosed |
| US-20190262269-A1 | Active-Targeting-Type Polymer Derivative, Composition Containing Said Polymer Derivative, And Uses Of Said Polymer Derivative And Said Composition | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2019-08-29 | — | — | US | disclosed |
| US-10357573-B2 | Block copolymer conjugate of physiologically active substance | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2019-07-23 | — | — | US | disclosed |
| EP-0560330-A2 | Substituted benzimidazolyl derivatives, therapeutic agents containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-09-15 | — | — | EP | disclosed |
| EP-0556789-A2 | Substituted biphenyl derivatives, therapeutic agents containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-08-25 | — | — | EP | disclosed |
| EP-0502314-A1 | Benzimidazol, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-09 | — | — | EP | disclosed |
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |
| US-4595696-A | Antiinflammatory agents; amide substituted phenyl ethers or thioethers | USV PHARMACEUTICAL CORP. (US) | 1986-06-17 | — | — | US | disclosed |
| US-4533554-A | ANALGESICS, HYPOTENSIVE AGENTS, ANTI-INFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-08-06 | — | — | US | disclosed |
| US-4388312-A | HYPOTENSIVE AGENTS, ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-06-14 | — | — | US | disclosed |
| EP-0025692-B1 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1982-12-01 | — | — | EP | disclosed |
| EP-0025692-A1 | Quinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-03-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190307905-A1 | Novel Polymer Derivatives, And Novel Polymer Derivative Imaging Probe Using Same | MPI, ACP1, PDAP1 | EPHX1 3995/4885NPC1 3687/4885SMN1; SMN2 2091/4885 |
| US-10869937-B2 | Polymer derivatives, and novel polymer derivative imaging probe using same | ERBB3, DDOST, EGFR | EPHX1 4185/4885NPC1 3627/4885SMN1; SMN2 2043/4885 |
| US-10973762-B2 | Active-targeting-type polymer derivative, composition containing said polymer derivative, and uses of said polymer derivative and said composition | CD68, HPGDS, MYD88 | EPHX1 2390/4885NPC1 2814/4885SMN1; SMN2 3923/4885 |
| US-20190262269-A1 | Active-Targeting-Type Polymer Derivative, Composition Containing Said Polymer Derivative, And Uses Of Said Polymer Derivative And Said Composition | CD68, HPGDS, MYD88 | EPHX1 2390/4885NPC1 2814/4885SMN1; SMN2 3923/4885 |
| US-10814016-B2 | — | ERBB3, ERBB2, EGFR | EPHX1 3691/4885NPC1 3535/4885SMN1; SMN2 849/4885 |
| US-10357573-B2 | Block copolymer conjugate of physiologically active substance | TACR1, PLAUR, LNPEP | EPHX1 2636/4885NPC1 3884/4885SMN1; SMN2 2711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.