Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.35 |
| ▸ | ITGAV | P06756 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27558585 | 0.87 | KDM4E (0.38) | CCR2L3MBTL1TSHRKDM4EMEN1 | |
| SCHEMBL7470398 | 0.81 | ITGB3 (0.51) | CCR2TSHRKDM4EMEN1KMT2A | |
| SCHEMBL7048411 | 0.81 | ITGB3 (0.51) | CCR2TSHRKDM4EMEN1KMT2A | |
| SCHEMBL7461670 | 0.81 | ITGB3 (0.58) | ITGB3ITGA2BITGAV | |
| SCHEMBL382763 | 0.80 | ITGB3 (0.48) | KDM4EHTTITGB3ITGA2BITGAV | |
| SCHEMBL382545 | 0.79 | ITGB3 (0.46) | KDM4EHTTITGB3ITGA2BITGAV | |
| SCHEMBL382702 | 0.79 | ITGB3 (0.46) | KDM4EHTTITGB3ITGA2BITGAV | |
| SCHEMBL7468819 | 0.79 | KAT6A (0.43) | L3MBTL1SMN1; SMN2ITGB3ITGA2BITGAV | |
| SCHEMBL7462239 | 0.79 | ITGB3 (0.49) | CCR2L3MBTL1TSHRKDM4EMEN1 | |
| SCHEMBL7470189 | 0.79 | GRIN2B (0.36) | L3MBTL1KDM4ERAB9AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | claimed |
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |