Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 5/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | USP5 | P45974 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466504 | 0.91 | RAB9A (0.36) | GRIN2BKAT6AKDM4EHTTALDH1A1 | |
| SCHEMBL7468819 | 0.87 | KAT6A (0.43) | GRIN2BKAT6AALDH1A1L3MBTL1 | |
| SCHEMBL6498054 | 0.84 | RAB9A (0.34) | GRIN2BKDM4EHTTALDH1A1L3MBTL1 | |
| SCHEMBL6503828 | 0.82 | ITGB3 (0.49) | — | |
| SCHEMBL7457979 | 0.81 | SFRP1 (0.42) | KAT6AKDM4EHTTALDH1A1 | |
| SCHEMBL7050609 | 0.79 | KAT6A (0.38) | KAT6AKDM4EHTTALDH1A1L3MBTL1 | |
| SCHEMBL7464729 | 0.79 | CCR2 (0.38) | GRIN2BKDM4EHTTALDH1A1L3MBTL1 | |
| SCHEMBL7463691 | 0.78 | KDM4E (0.52) | KAT6AKDM4EHTTALDH1A1RAB9A | |
| SCHEMBL7474930 | 0.78 | ITGB3 (0.43) | KAT6AKDM4EHTTRAB9A | |
| SCHEMBL7469429 | 0.78 | ITGB3 (0.43) | KAT6AKDM4EHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229024-A1 | m-SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING INTEGRIN ALPHA-V BETA-3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-08-07 | — | — | EP | claimed |
| EP-1229024-A1 | m-SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING INTEGRIN ALPHA-V BETA-3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-08-07 | — | — | EP | disclosed |