Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28105264 | 0.86 | HTT (0.52) | SMN1; SMN2HTTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL20488351 | 0.85 | KMT2A (0.55) | SMN1; SMN2ALDH1A1KMT2ANPC1LMNA | |
| SCHEMBL1902358 | 0.84 | SMN1; SMN2 (0.76) | SMN1; SMN2HTTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL3488361 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2HTTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL7460811 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KMT2AL3MBTL1LMNAHPGD | |
| SCHEMBL31581689 | 0.81 | S1PR5 (0.59) | SMN1; SMN2HTTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL16880646 | 0.80 | HTT (0.46) | SMN1; SMN2HTTALDH1A1KMT2ANPC1 | |
| SCHEMBL18956194 | 0.79 | HPGD (0.50) | SMN1; SMN2HTTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL2222168 | 0.78 | HPGD (0.53) | SMN1; SMN2ALDH1A1KMT2AL3MBTL1NPC1 | |
| SCHEMBL20676018 | 0.78 | SMN1; SMN2 (0.85) | SMN1; SMN2HTTALDH1A1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1180513-A1 | CYCLIC AMIDE COMPOUNDS, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-02-20 | — | — | EP | disclosed |