Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377981 | 0.86 | MEN1 (0.52) | MEN1KMT2AALDH1A1POLBHTT | |
| SCHEMBL7470844 | 0.83 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1POLBHTT | |
| SCHEMBL7468160 | 0.80 | DPP4 (0.56) | MEN1KMT2AALDH1A1POLBHTT | |
| SCHEMBL7051582 | 0.80 | DPP4 (0.56) | MEN1KMT2AALDH1A1POLBHTT | |
| SCHEMBL21135456 | 0.79 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1POLBHTT | |
| SCHEMBL21135449 | 0.79 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1POLBHTT | |
| SCHEMBL21135497 | 0.79 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1POLBHTT | |
| SCHEMBL23839398 | 0.78 | HTT (0.50) | MEN1KMT2AALDH1A1POLBHTT | |
| SCHEMBL23839396 | 0.78 | HTT (0.50) | MEN1KMT2AALDH1A1POLBHTT | |
| SCHEMBL1096771 | 0.78 | TDP1 (0.55) | MEN1KMT2AALDH1A1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |