Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 10/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460529 | 0.90 | SLC6A2 (0.43) | PDGFRAKDRMETSLC6A2SLC6A4 | |
| SCHEMBL7050110 | 0.89 | EGFR (0.41) | TRPA1KDRHTR1ASLC6A2SLC6A4 | |
| SCHEMBL7532122 | 0.85 | NR4A2 (0.40) | SLC6A2SLC6A3 | |
| Quinoxyfen SCHEMBL28247243 | 0.83 | RET (0.42) | TRPA1RETPDGFRAKDRMET | |
| Quinoxyfen SCHEMBL22257 | 0.83 | RET (0.42) | TRPA1RETPDGFRAKDRMET | |
| Quinoxyfen SCHEMBL7471425 | 0.82 | RET (0.41) | TRPA1RETPDGFRAKDRMET | |
| Quinoxyfen SCHEMBL1974400 | 0.82 | RET (0.41) | TRPA1RETPDGFRAKDRMET | |
| SCHEMBL7461330 | 0.81 | RHEB (0.46) | SLC6A2SLC6A4SLC6A3MAP4K4 | |
| SCHEMBL16188289 | 0.81 | CCNT1 (0.39) | TRPA1PDGFRAKDRSLC6A2SLC6A4 | |
| SCHEMBL8071596 | 0.81 | DHFR (0.50) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | claimed |
| US-5145843-A | For plants | DOWELANCO (US) | 1992-09-08 | — | — | US | claimed |