Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13685213 | 0.91 | MAPK1 (0.52) | MAPK1TP53RAB9AHTR7TDP1 | |
| SCHEMBL7391962 | 0.87 | TP53 (0.67) | MAPK1TP53RAB9AHTR7TDP1 | |
| SCHEMBL11023081 | 0.85 | TP53 (0.65) | MAPK1TP53RAB9AHTR7L3MBTL1 | |
| SCHEMBL13739595 | 0.84 | TP53 (0.74) | MAPK1TP53RAB9AHTR7TDP1 | |
| SCHEMBL14280096 | 0.84 | MAPK1 (0.62) | MAPK1TP53RAB9AHTR7TDP1 | |
| SCHEMBL9482701 | 0.84 | TP53 (0.62) | MAPK1TP53RAB9AHTR7ADRB2 | |
| SCHEMBL7459616 | 0.84 | L3MBTL1 (0.45) | MAPK1TP53RAB9AHTR7TDP1 | |
| SCHEMBL13685212 | 0.84 | MAPK1 (0.44) | MAPK1TP53RAB9AHTR7TDP1 | |
| SCHEMBL11021406 | 0.82 | TP53 (0.61) | MAPK1TP53RAB9AHTR7ADRB2 | |
| SCHEMBL11017378 | 0.82 | TP53 (0.61) | MAPK1TP53RAB9AHTR7ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | claimed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | claimed |
| US-4067896-A | ANTIMICROBIAL, HERBICIDES, FUNGICIDES, INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1978-01-10 | — | — | US | disclosed |