Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466248 | 0.95 | NR4A2 (0.47) | NR4A2SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL7458613 | 0.87 | NR4A2 (0.54) | NR4A2SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL7464651 | 0.87 | NR4A2 (0.47) | NR4A2SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL7531657 | 0.85 | NR4A2 (0.59) | NR4A2SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL7461344 | 0.85 | NR4A2 (0.46) | NR4A2SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL7458649 | 0.82 | NR4A2 (0.49) | NR4A2SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL7458700 | 0.81 | NR4A2 (0.45) | NR4A2SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL7460036 | 0.81 | KDM4E (0.46) | NR4A2SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL7464893 | 0.81 | NR4A2 (0.47) | NR4A2SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL7461771 | 0.80 | NR4A2 (0.44) | NR4A2SMN1; SMN2KDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | claimed |
| US-5145843-A | For plants | DOWELANCO (US) | 1992-09-08 | — | — | US | claimed |
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | disclosed |