SCHEMBL7464651

SCHEMBL7464651

Cc1ccccc1Oc1ccnc2c(Cl)cccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.44
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
HTT P42858 1/20 0.42
HSD17B10 Q99714 1/20 0.42
AR P10275 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
MEN1 O00255 1/20 0.40
TSHR P16473 1/20 0.40
KMT2A Q03164 1/20 0.40
NR1H2 P55055 1/20 0.39
NR1H3 Q13133 1/20 0.39
HTR1A P08908 1/20 0.38
ADRA1D P25100 1/20 0.38
ADRA1A P35348 1/20 0.38
ADRA1B P35368 1/20 0.38
GAA P10253 2/20 0.38
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7461344 0.90 NR4A2 (0.46) NR4A2SMN1; SMN2KDM4EALDH1A1HTT
SCHEMBL7466638 0.88 NR4A2 (0.53) NR4A2SMN1; SMN2KDM4EALDH1A1HTT
SCHEMBL7531657 0.87 NR4A2 (0.59) NR4A2SMN1; SMN2KDM4EALDH1A1HTT
SCHEMBL7465004 0.87 NR4A2 (0.49) NR4A2SMN1; SMN2KDM4EALDH1A1HTT
SCHEMBL7467276 0.86 NR4A2 (0.43) NR4A2SMN1; SMN2KDM4EALDH1A1HTT
SCHEMBL7458700 0.86 NR4A2 (0.45) NR4A2SMN1; SMN2KDM4EALDH1A1HTT
SCHEMBL7461220 0.85 NR4A2 (0.47) NR4A2SMN1; SMN2KDM4EALDH1A1HTT
SCHEMBL7466248 0.85 NR4A2 (0.47) NR4A2SMN1; SMN2KDM4EALDH1A1HTT
SCHEMBL7467251 0.85 NR4A2 (0.48) NR4A2SMN1; SMN2KDM4EALDH1A1HTT
SCHEMBL7464982 0.83 L3MBTL1 (0.46) NR4A2SMN1; SMN2KDM4EALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0326330-B1 Quinoline fungicides DOW AGROSCIENCES LLC (US) 2002-07-24 EP claimed
US-5145843-A For plants DOWELANCO (US) 1992-09-08 US claimed
EP-0326330-B1 Quinoline fungicides DOW AGROSCIENCES LLC (US) 2002-07-24 EP disclosed