Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.47 |
| ▸ | KDR | P35968 | 4/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462623 | 0.88 | LMNA (0.54) | APPMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7461823 | 0.86 | APP (0.58) | APPSMN1; SMN2LMNAPDGFRAKDR | |
| SCHEMBL7461223 | 0.86 | LMNA (0.52) | APPMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10377143 | 0.85 | POLB (0.63) | APPMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7462609 | 0.83 | FGFR2 (0.59) | APPMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7456971 | 0.83 | NR4A2 (0.51) | APPMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7465918 | 0.83 | LMNA (0.49) | APPMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7466509 | 0.83 | LMNA (0.49) | APPMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7466387 | 0.83 | NR4A2 (0.55) | APPMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7465843 | 0.83 | MAPT (0.55) | APPMAPTSMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | disclosed |