Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.49 |
| ▸ | KDR | P35968 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MET | P08581 | 5/20 | 0.48 |
| ▸ | AXL | P30530 | 4/20 | 0.48 |
| ▸ | MERTK | Q12866 | 3/20 | 0.48 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27295456 | 0.99 | NR4A2 (0.50) | NR4A2SOS2PDGFRAKDRLMNA | |
| SCHEMBL7462623 | 0.91 | LMNA (0.54) | NR4A2SOS2PDGFRAKDRLMNA | |
| SCHEMBL7482722 | 0.90 | MET (0.54) | PDGFRAKDRLMNASMN1; SMN2MET | |
| SCHEMBL7460943 | 0.88 | PDGFRA (0.56) | PDGFRAKDRMETAXLMERTK | |
| SCHEMBL7470574 | 0.86 | KDR (0.49) | NR4A2SOS2PDGFRAKDRLMNA | |
| SCHEMBL7465843 | 0.85 | MAPT (0.55) | NR4A2SOS2PDGFRAKDRLMNA | |
| SCHEMBL7461823 | 0.85 | APP (0.58) | PDGFRAKDRLMNASMN1; SMN2APP | |
| SCHEMBL7465918 | 0.85 | LMNA (0.49) | NR4A2SOS2PDGFRAKDRLMNA | |
| SCHEMBL7461223 | 0.85 | LMNA (0.52) | NR4A2SOS2PDGFRAKDRLMNA | |
| SCHEMBL29453809 | 0.85 | NR4A2 (0.55) | NR4A2SOS2PDGFRAKDRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | claimed |
| US-5145843-A | For plants | DOWELANCO (US) | 1992-09-08 | — | — | US | claimed |
| CN-109232417-B | Preparation method of 4-phenoxyl quinoline compound | 浙江工业大学 | 2021-02-09 | — | — | CN | disclosed |
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | disclosed |
| CN-1031263-C | Quinoline, quinazoline, and cinnoline | LILLY CO ELI (US) | 1996-03-13 | — | — | CN | disclosed |
| EP-0569021-A1 | Process for the preparation of 4-phenoxyquinoline compounds | DOWELANCO (US) | 1993-11-10 | — | — | EP | disclosed |
| US-5245036-A | Process for the preparation of 4-phenoxyquinoline compounds | DOWELANCO (US) | 1993-09-14 | — | — | US | disclosed |
| US-5240940-A | Synergistic nmixture | DOWELANCO (US) | 1993-08-31 | — | — | US | disclosed |
| US-5145843-A | For plants | DOWELANCO (US) | 1992-09-08 | — | — | US | disclosed |
| CN-1034925-A | Quinoline, quinazoline and cinnoline | LILLY CO ELI (US) | 1989-08-23 | — | — | CN | disclosed |
| EP-0326330-A2 | Quinoline, quinazoline, and cinnoline fungicides | DowElanco (US) | 1989-08-02 | — | — | EP | disclosed |