Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 2/20 | 0.52 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | LSS | P48449 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472599 | 0.88 | L3MBTL3 (0.52) | L3MBTL3ABL1RIN1KMT2AACHE | |
| Hydrochloric Acid SCHEMBL7476858 | 0.88 | L3MBTL3 (0.52) | L3MBTL3ABL1RIN1KMT2AACHE | |
| SCHEMBL8106205 | 0.88 | ALDH1A1 (0.56) | L3MBTL3ABL1RIN1KMT2AACHE | |
| Hydrochloric Acid SCHEMBL7474861 | 0.87 | ALDH1A1 (0.55) | L3MBTL3ABL1RIN1KMT2AACHE | |
| Oxalic Acid SCHEMBL7470413 | 0.86 | KMT2A (0.57) | L3MBTL3KMT2ALSSMEN1L3MBTL1 | |
| SCHEMBL7466231 | 0.86 | L3MBTL3 (0.50) | L3MBTL3ABL1RIN1KMT2ALMNA | |
| SCHEMBL7475777 | 0.86 | MCHR1 (0.52) | L3MBTL3ABL1RIN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL7472960 | 0.86 | L3MBTL3 (0.47) | L3MBTL3ABL1RIN1KMT2AACHE | |
| Hydrochloric Acid SCHEMBL7474764 | 0.85 | L3MBTL3 (0.49) | L3MBTL3ABL1RIN1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7471203 | 0.85 | ABL1 (0.52) | L3MBTL3ABL1RIN1KMT2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650476-B1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMA CO LTD (JP) | 2002-06-26 | — | — | EP | disclosed |
| US-6136826-A | AMINOPIPERIDINE COMPOUNDS SUBSTITUTED WITH ALKANOYL | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| US-5656642-A | Peripheral vasodilating agent containing piperidine derivative as active ingredient | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| EP-0650476-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994022826-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |