Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.68 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.68 |
| ▸ | PDE1A | P54750 | 1/20 | 0.59 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.59 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | UBE2N | P61088 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.52 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459561 | 0.91 | POLB (0.65) | POLBHIF1ASMN1; SMN2RXFP1ADORA2B | |
| SCHEMBL7606543 | 0.90 | POLB (0.57) | POLBHIF1ASMN1; SMN2RXFP1ADORA2B | |
| SCHEMBL7603292 | 0.88 | POLB (0.74) | POLBHIF1ASMN1; SMN2RXFP1ADORA2B | |
| SCHEMBL7603804 | 0.88 | POLB (0.67) | POLBHIF1ASMN1; SMN2RXFP1ADORA2B | |
| SCHEMBL7604677 | 0.88 | POLB (0.67) | POLBHIF1ASMN1; SMN2RXFP1ADORA2B | |
| SCHEMBL11014928 | 0.87 | POLB (0.83) | POLBHIF1ASMN1; SMN2RXFP1ADORA2B | |
| SCHEMBL7608447 | 0.84 | POLB (0.67) | POLBHIF1ASMN1; SMN2RXFP1ADORA2B | |
| SCHEMBL5718879 | 0.82 | POLB (0.65) | POLBHIF1ASMN1; SMN2RXFP1ADORA2B | |
| SCHEMBL7608305 | 0.82 | POLB (0.75) | POLBHIF1ASMN1; SMN2RXFP1ADORA2B | |
| SCHEMBL1944405 | 0.81 | ADORA2B (1.00) | POLBHIF1ASMN1; SMN2RXFP1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812844-B1 | Use of theophyllin derivatives for the treatment and prophylaxis fo shock conditions, novel xanthine compounds and processes for the production thereof | HOECHST AG (DE) | 2002-10-23 | — | — | EP | claimed |
| EP-0771813-B1 | Alkylxanthine phosphonates and alkylxanthine phosphine oxydes and their use as medicines | HOECHST AG (DE) | 2002-01-16 | — | — | EP | disclosed |
| US-5728686-A | TREATMENT OF MUSCULAR DYSTROPHY | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-17 | — | — | US | disclosed |
| EP-0771813-A1 | Alkylxanthine phosphonates and alkylxanthine phosphine oxydes and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-07 | — | — | EP | disclosed |