Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465788 | 0.92 | MAOB (0.47) | MAOBHIF1AFFAR1SPHK2SPHK1 | |
| SCHEMBL7742091 | 0.92 | MAOB (0.47) | MAOBHIF1AFFAR1SPHK2SPHK1 | |
| SCHEMBL7467521 | 0.92 | MAOB (0.40) | MAOBHIF1APPARAALDH1A1MAPT | |
| SCHEMBL7470568 | 0.92 | MAPK14 (0.38) | MAOBHIF1APPARAPPARGATM | |
| SCHEMBL7470227 | 0.91 | HIF1A (0.42) | MAOBHIF1APPARAPOLBRAB9A | |
| SCHEMBL8544101 | 0.86 | MAOB (0.45) | MAOBHIF1AFFAR1SPHK2SPHK1 | |
| SCHEMBL8538076 | 0.86 | MAOB (0.45) | MAOBHIF1AFFAR1SPHK2SPHK1 | |
| SCHEMBL7467262 | 0.85 | MAPK14 (0.39) | HIF1AMAPT | |
| SCHEMBL7465129 | 0.84 | MAOB (0.43) | MAOBHIF1ASLC6A5PPARAFFAR1 | |
| SCHEMBL7465132 | 0.84 | MAOB (0.43) | MAOBHIF1ASLC6A5PPARAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865424-B1 | PESTICIDES | BAYER AG (DE) | 2002-09-18 | — | — | EP | disclosed |
| EP-0865424-A1 | PESTICIDES | Novartis AG (CH) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020809-A1 | PESTICIDES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |