Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 19/20 | 0.80 |
| ▸ | BCR | P11274 | 16/20 | 0.80 |
| ▸ | PRKCA | P17252 | 8/20 | 0.80 |
| ▸ | SRC | P12931 | 9/20 | 0.79 |
| ▸ | PRKCD | Q05655 | 6/20 | 0.76 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.76 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.76 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.74 |
| ▸ | PRKCG | P05129 | 1/20 | 0.74 |
| ▸ | PRKCB | P05771 | 1/20 | 0.74 |
| ▸ | PRKCH | P24723 | 1/20 | 0.74 |
| ▸ | PRKCI | P41743 | 1/20 | 0.74 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.74 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.74 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.74 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.74 |
| ▸ | EGFR | P00533 | 3/20 | 0.67 |
| ▸ | PRKACA | P17612 | 1/20 | 0.67 |
| ▸ | PRKACG | P22612 | 1/20 | 0.67 |
| ▸ | PRKACB | P22694 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1655099 | 0.89 | ABL1 (1.00) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL1927119 | 0.88 | ABL1 (1.00) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL4895454 | 0.88 | ABL1 (0.80) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL14088818 | 0.88 | ABL1 (0.80) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL7468958 | 0.88 | ABL1 (0.76) | ABL1BCRPRKCASRCPRKCD | |
| Hydrochloric Acid SCHEMBL27711429 | 0.87 | ABL1 (0.79) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL11924749 | 0.87 | ABL1 (0.62) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL7467179 | 0.86 | ABL1 (0.69) | ABL1BCRPRKCASRCPRKCD | |
| SCHEMBL1522 | 0.86 | ABL1 (1.00) | ABL1BCRPRKCASRCPRKCD | |
| Hydrochloric Acid SCHEMBL27708725 | 0.86 | ABL1 (0.77) | ABL1BCRPRKCASRCPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080187575-A1 | Pyrimidine Derivatives | VICHEM CHEMIE KFT (HU) | 2008-08-07 | — | — | US | disclosed |
| EP-0233461-B2 | 4,5,6-Substituted-2-pyrimidinamines | AMERICAN CYANAMID CO (US) | 2002-05-29 | — | — | EP | disclosed |
| EP-0233461-B1 | 4,5,6-Substituted-2-pyrimidinamines | AMERICAN CYANAMID CO (US) | 1996-03-20 | — | — | EP | disclosed |
| US-4876252-A | ADMINISTERING ANTIASTHMATIC OR ANTIALLERGEN | AMERICAN CYANAMID COMPANY (US) | 1989-10-24 | — | — | US | disclosed |
| US-4788195-A | TREATING ASTHMA, ALLERGIC DISEASES, INFLAMMATION AND DIABETES IN MAMMALS | AMERICAN CYANAMID COMPANY (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0233461-A2 | 4,5,6-Substituted-2-pyrimidinamines | AMERICAN CYANAMID COMPANY (US) | 1987-08-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080187575-A1 | Pyrimidine Derivatives | TYMP, TDP1, PNP | ABL1 2843/4885BCR 2315/4885PRKCA 2607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.