Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 3/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784564 | 0.83 | MEN1 (0.72) | HTR6KMT2AMEN1FABP4 | |
| SCHEMBL27292211 | 0.83 | HTR6 (0.58) | HTR6FABP4NR4A2 | |
| Hydrochloric Acid SCHEMBL7469779 | 0.82 | HTR6 (0.56) | HTR6FABP4NR4A2 | |
| SCHEMBL7469773 | 0.82 | HTR6 (0.56) | HTR6FABP4HTR3A | |
| SCHEMBL10708955 | 0.81 | MEN1 (0.58) | HTR6KMT2AMEN1FABP4KDM4E | |
| SCHEMBL22805900 | 0.79 | PIK3C3 (0.42) | HTR6KMT2AMEN1NR4A2KDM4E | |
| SCHEMBL701556 | 0.78 | NR4A2 (0.64) | KMT2AMEN1NR4A2MAPTHSP90AA1 | |
| SCHEMBL31607540 | 0.78 | NR4A2 (0.64) | KMT2AMEN1NR4A2MAPTHSP90AA1 | |
| SCHEMBL3222576 | 0.77 | NR4A2 (0.50) | KMT2AMEN1NR4A2MAPTHSP90AA1 | |
| SCHEMBL11218801 | 0.77 | NR4A2 (0.50) | KMT2AMEN1NR4A2MAPTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636622-B1 | Isoxazole derivatives and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-23 | — | — | EP | disclosed |
| EP-1160244-A1 | Isoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2001-12-05 | — | — | EP | disclosed |
| US-5489570-A | PRE- OR POST-EMERGENCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-02-06 | — | — | US | disclosed |
| EP-0636622-A1 | Isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-02-01 | — | — | EP | disclosed |