Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 3/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475682 | 0.87 | CYP2C9 (0.33) | NTRK1SCN9A | |
| SCHEMBL7475914 | 0.84 | MAPK14 (0.41) | MAPK14KMT2AMRGPRX4NR1H2NR1H3 | |
| SCHEMBL7480550 | 0.80 | KDM4E (0.35) | HTTHSD17B10 | |
| SCHEMBL7478426 | 0.78 | MAPK14 (0.36) | MAPK14KMT2A | |
| SCHEMBL7469263 | 0.76 | GRM4 (0.34) | MAPK14 | |
| SCHEMBL7463562 | 0.72 | NR1H2 (0.47) | KMT2AMRGPRX4NR1H2NR1H3SCN9A | |
| SCHEMBL7475655 | 0.72 | CYP2C9 (0.34) | KMT2A | |
| SCHEMBL7477958 | 0.72 | CYP2D6 (0.33) | KMT2A | |
| SCHEMBL7472346 | 0.71 | LMNA (0.36) | NTRK1MAPK14KMT2ANR1H2NR1H3 | |
| SCHEMBL7472090 | 0.69 | CYP2C9 (0.37) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077701-A4 | ANTI-VIRAL COMPOUNDS | LILLY CO ELI (US) | 2002-03-20 | — | — | EP | disclosed |
| EP-1077701-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059587-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |