Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F12 | P00748 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | IDH2 | P48735 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474172 | 0.85 | KDR (0.35) | KDM4EALDH1A1KDRLMNAPOLB | |
| SCHEMBL7478426 | 0.85 | MAPK14 (0.36) | ALDH1A1LMNAPOLBGAAHPGD | |
| SCHEMBL7476794 | 0.84 | HSD17B10 (0.41) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL7465263 | 0.80 | NTRK1 (0.31) | HSD17B10HTT | |
| SCHEMBL7470913 | 0.78 | HTT (0.41) | KDM4EALDH1A1LMNAPOLBGAA | |
| SCHEMBL7472090 | 0.73 | CYP2C9 (0.37) | ALDH1A1F2F12RAB9A | |
| SCHEMBL7469263 | 0.73 | GRM4 (0.34) | F2F12NPC1RAB9A | |
| SCHEMBL7477958 | 0.72 | CYP2D6 (0.33) | LMNAGAAHPGDF2F12 | |
| SCHEMBL7473148 | 0.69 | MAPK14 (0.44) | ALDH1A1LMNAPOLBGAANPC1 | |
| SCHEMBL7479307 | 0.69 | GLA (0.39) | KDM4EALDH1A1LMNAPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077701-A4 | ANTI-VIRAL COMPOUNDS | LILLY CO ELI (US) | 2002-03-20 | — | — | EP | disclosed |
| EP-1077701-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059587-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |