Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465969 | 0.90 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL7472475 | 0.78 | SMN1; SMN2 (0.81) | SMN1; SMN2ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL6081501 | 0.77 | POLB (0.51) | SMN1; SMN2ALDH1A1GAAMAPTNPC1 | |
| SCHEMBL9029757 | 0.72 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL16406345 | 0.71 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL7474447 | 0.70 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1MAPTNPC1LMNA | |
| SCHEMBL4893361 | 0.70 | KMT2A (0.60) | SMN1; SMN2ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL9760661 | 0.70 | MAPT (0.77) | SMN1; SMN2ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL12260740 | 0.70 | KMT2A (0.60) | SMN1; SMN2ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL546063 | 0.69 | ALDH1A1 (0.78) | SMN1; SMN2ALDH1A1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5852011-A | Benzimidazole derivatives | MITSUI CHEMICALS, INC. (JP) | 1998-12-22 | — | — | US | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |