Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 7/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469481 | 0.68 | — | — | |
| SCHEMBL7471758 | 0.62 | — | — | |
| SCHEMBL11839444 | 0.61 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL9354170 | 0.58 | — | — | |
| SCHEMBL6054462 | 0.56 | NISCH (0.69) | ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL9022322 | 0.55 | — | — | |
| SCHEMBL14253149 | 0.55 | — | — | |
| SCHEMBL11007474 | 0.55 | NISCH (0.58) | ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL11428144 | 0.55 | NISCH (0.55) | ADRA2AADRA2BADRA2CNISCH | |
| SCHEMBL11418621 | 0.55 | NISCH (0.55) | ADRA2AADRA2BADRA2CNISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416814-A2 | Cephalosporin compounds, process for their preparation, pharmaceutical compositions and intermediates | BEECHAM GROUP PLC (GB) | 1991-03-13 | — | — | EP | claimed |
| EP-0416814-B1 | Antibacterial cephalosporin derivatives | PFIZER (US) | 2002-04-24 | — | — | EP | disclosed |
| US-5504076-A | Cephalosporin compounds | PFIZER INC. (US) | 1996-04-02 | — | — | US | disclosed |
| EP-0416814-A2 | Cephalosporin compounds, process for their preparation, pharmaceutical compositions and intermediates | BEECHAM GROUP PLC (GB) | 1991-03-13 | — | — | EP | disclosed |