SCHEMBL7465488

SCHEMBL7465488

Nc1ccc(O)c(-c2ccccc2O)c1N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.53
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
TDP1 Q9NUW8 3/20 0.53
HPGD P15428 3/20 0.53
POLB P06746 2/20 0.53
MCL1 Q07820 2/20 0.53
CSNK1A1 P48729 2/20 0.53
CSNK1D P48730 2/20 0.53
CSNK1G1 Q9HCP0 2/20 0.53
PABPC1 P11940 1/20 0.53
BLM P54132 1/20 0.53
PLEC Q15149 1/20 0.53
MAOA P21397 5/20 0.46
MAOB P27338 2/20 0.46
ALOX15 P16050 2/20 0.44
TSHR P16473 2/20 0.44
MAPT P10636 3/20 0.43
HDAC3 O15379 1/20 0.43
IDO1 P14902 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29963645 1.00 SMN1; SMN2 (0.53) SMN1; SMN2MEN1KMT2ATDP1HPGD
SCHEMBL6576340 0.88 MEN1 (0.53) SMN1; SMN2MEN1KMT2ATDP1HPGD
SCHEMBL29660908 0.82 CSNK2A2 (0.56) SMN1; SMN2MEN1KMT2ATDP1HPGD
SCHEMBL28942714 0.82 CSNK2A2 (0.56) SMN1; SMN2MEN1KMT2ATDP1HPGD
SCHEMBL30136525 0.78 ALOX15 (0.54) SMN1; SMN2MEN1KMT2ATDP1HPGD
SCHEMBL2938819 0.78 ALOX15 (0.54) SMN1; SMN2MEN1KMT2ATDP1HPGD
SCHEMBL16962792 0.77 HSD17B10 (0.50) SMN1; SMN2MEN1KMT2ATDP1HPGD
SCHEMBL30434982 0.77 ALOX15 (0.52) SMN1; SMN2MEN1KMT2ATDP1HPGD
SCHEMBL498128 0.76 MEN1 (0.64) SMN1; SMN2MEN1KMT2ATDP1HPGD
SCHEMBL31183058 0.75 ALDH1A1 (0.46) SMN1; SMN2MEN1KMT2ATDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102558861-A Halogen-free phosphate-free high-heat-resistance thermosetting resin composition as well as bonding sheet and copper clad laminate prepared from same GUANGDONG SHENGYI SCI TECH CO 2012-07-11 CN claimed
CN-115141370-A Polyimide, metal-clad laminate, and circuit board 日铁化学材料株式会社 2022-10-04 CN disclosed
CN-103228739-A Azo dyes KEMIRA OYJ 2013-07-31 CN disclosed
CN-102558861-A Halogen-free phosphate-free high-heat-resistance thermosetting resin composition as well as bonding sheet and copper clad laminate prepared from same GUANGDONG SHENGYI SCI TECH CO 2012-07-11 CN disclosed
CN-102325824-A Fluorinated dicarboxylic acid derivative and polymer compound using same CENTRAL GLASS CO LTD 2012-01-18 CN disclosed
EP-1208077-A1 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS Wella Aktiengesellschaft (DE) 2002-05-29 EP disclosed
WO-2002002507-A1 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS WELLA AKTIENGESELLSCHAFT (DE) 2002-01-10 WO disclosed