Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7466563 | 0.99 | SIGMAR1 (0.53) | SIGMAR1MCHR1MEN1TP53CYP1A2 | |
| SCHEMBL7468176 | 0.87 | MCHR1 (0.48) | SIGMAR1MCHR1DRD2 | |
| Hydrochloric Acid SCHEMBL7463940 | 0.87 | MCHR1 (0.47) | SIGMAR1MCHR1DRD2 | |
| SCHEMBL7462387 | 0.86 | MCHR1 (0.46) | SIGMAR1MCHR1MEN1TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL7461139 | 0.85 | MCHR1 (0.45) | SIGMAR1MCHR1MEN1TP53CYP1A2 | |
| SCHEMBL7468859 | 0.85 | CYP2C19 (0.54) | SIGMAR1MCHR1MEN1TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL7467161 | 0.84 | CYP2C19 (0.55) | SIGMAR1MCHR1MEN1TP53CYP1A2 | |
| SCHEMBL7466062 | 0.84 | CHRM2 (0.61) | MCHR1MEN1TP53CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL7460883 | 0.83 | CHRM2 (0.60) | MCHR1MEN1TP53CYP3A4CYP2D6 | |
| SCHEMBL7466510 | 0.82 | MCHR1 (0.61) | SIGMAR1MCHR1MEN1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | claimed |
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |