Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7467161 | 0.99 | CYP2C19 (0.55) | CYP2C19ALDH1A1MCHR1KCNA3SIGMAR1 | |
| SCHEMBL7465626 | 0.85 | SIGMAR1 (0.54) | CYP2C19MCHR1KCNA3SIGMAR1CARM1 | |
| Hydrochloric Acid SCHEMBL7466563 | 0.84 | SIGMAR1 (0.53) | CYP2C19MCHR1KCNA3SIGMAR1CARM1 | |
| SCHEMBL7462387 | 0.81 | MCHR1 (0.46) | CYP2C19MCHR1KCNA3SIGMAR1CARM1 | |
| Hydrochloric Acid SCHEMBL7461139 | 0.80 | MCHR1 (0.45) | CYP2C19MCHR1KCNA3SIGMAR1CARM1 | |
| SCHEMBL7459851 | 0.80 | GLA (0.56) | CYP2C19ALDH1A1MCHR1TSHRKMT2A | |
| Hydrochloric Acid SCHEMBL7456232 | 0.79 | GLA (0.55) | CYP2C19ALDH1A1MCHR1TSHRKMT2A | |
| SCHEMBL7466062 | 0.78 | CHRM2 (0.61) | MCHR1TSHRKMT2AMEN1TP53 | |
| Hydrochloric Acid SCHEMBL7460883 | 0.78 | CHRM2 (0.60) | MCHR1TSHRKMT2AMEN1TP53 | |
| SCHEMBL7468176 | 0.76 | MCHR1 (0.48) | MCHR1SIGMAR1DRD2CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | claimed |
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |