Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 4/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16727043 | 0.82 | L3MBTL1 (0.48) | L3MBTL1HTR6ALDH1A1BRD4EPHX1 | |
| SCHEMBL16727042 | 0.81 | L3MBTL1 (0.47) | L3MBTL1HTR6EPHX1SMN1; SMN2 | |
| SCHEMBL30458168 | 0.81 | L3MBTL1 (0.47) | L3MBTL1HTR6BRD4EPHX1 | |
| SCHEMBL16727069 | 0.80 | L3MBTL1 (0.46) | L3MBTL1HTR6BRD4EPHX1 | |
| SCHEMBL31242702 | 0.80 | PPARG (0.47) | L3MBTL1HTR6MAPTALDH1A1BRD4 | |
| SCHEMBL13679140 | 0.80 | HTR6 (0.50) | L3MBTL1HTR6MAPTALDH1A1LMNA | |
| SCHEMBL27807484 | 0.79 | MAPT (0.40) | L3MBTL1HTR6MAPTALDH1A1LMNA | |
| SCHEMBL16727066 | 0.79 | L3MBTL1 (0.46) | L3MBTL1HTR6MAPTEPHX1 | |
| SCHEMBL2845690 | 0.79 | L3MBTL1 (0.47) | L3MBTL1HTR6MAPTALDH1A1LMNA | |
| SCHEMBL22153097 | 0.78 | L3MBTL1 (0.67) | L3MBTL1HTR6BRD4EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944596-B1 | 1-ACRYLOYLINDOLINE DERIVATIVES AND THEIR USE AS PRODRUGS OF ANTICANCER AGENTS | AUCKLAND UNISERVICES LTD (NZ) | 2002-10-16 | — | — | EP | disclosed |
| US-6251933-B1 | AMINO DERIVATIVES OF THE GENERAL CLASS OF CYCLOPROPYLINDOLES AND THEIR SECO PRECURSORS, AND USEFUL AS PRODRUG FOR ANTIBODY-DIRECTED ENZYME-PRODRUG THERAPY AND GENE-DIRECTED ENZYME-PRODRUG THERAPY FOR CANCER | THE CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2001-06-26 | — | — | US | disclosed |
| EP-0944596-A1 | SECO PRECURSORS OF CYCLOPROPYLINDOLINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025898-A1 | SECO PRECURSORS OF CYCLOPROPYLINDOLINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1998-06-18 | — | — | WO | disclosed |