Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27480601 | 0.96 | LMNA (0.60) | LMNATSHRKDM4EMAPK1ALDH1A1 | |
| SCHEMBL15344554 | 0.91 | LMNA (0.68) | LMNATSHRKDM4EMAPK1ALDH1A1 | |
| SCHEMBL7472353 | 0.88 | KDM4E (0.56) | LMNATSHRKDM4EMAPK1NPC1 | |
| SCHEMBL7471813 | 0.87 | LMNA (0.57) | LMNATSHRKDM4EALDH1A1TDP1 | |
| SCHEMBL7530948 | 0.86 | LMNA (0.55) | LMNATSHRKDM4EALDH1A1TDP1 | |
| SCHEMBL7464858 | 0.86 | LMNA (0.55) | LMNATSHRKDM4EALDH1A1TDP1 | |
| SCHEMBL7471305 | 0.84 | LMNA (0.54) | LMNATSHRKDM4EALDH1A1TDP1 | |
| SCHEMBL27428199 | 0.84 | LMNA (0.57) | LMNATSHRKDM4EALDH1A1TDP1 | |
| SCHEMBL7464641 | 0.83 | KMT2A (0.61) | LMNAKDM4EALDH1A1ESR1POLB | |
| SCHEMBL18775890 | 0.82 | LMNA (0.58) | LMNATSHRKDM4EMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859774-B1 | SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES | BAYER AG (DE) | 2002-04-03 | — | — | EP | disclosed |
| EP-0859774-A1 | SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES | BAYER AG (DE) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997016449-A1 | SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-05-09 | — | — | WO | disclosed |