Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.44 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27425790 | 0.96 | LMNA (0.57) | LMNAALDH1A1CYP4F2CYP4A11TSHR | |
| SCHEMBL3033016 | 0.91 | LMNA (0.66) | LMNAALDH1A1CYP4F2CYP4A11TSHR | |
| SCHEMBL7473301 | 0.88 | CYP4F2 (0.61) | LMNAALDH1A1CYP4F2CYP4A11TSHR | |
| SCHEMBL7471813 | 0.87 | LMNA (0.57) | LMNAALDH1A1TSHRESR1CHRM1 | |
| SCHEMBL7530948 | 0.86 | LMNA (0.55) | LMNAALDH1A1TSHRESR1CHRM1 | |
| SCHEMBL7465769 | 0.86 | LMNA (0.59) | LMNAALDH1A1TSHRESR1CHRM1 | |
| SCHEMBL13291593 | 0.85 | CYP4F2 (0.62) | LMNAALDH1A1CYP4F2CYP4A11TSHR | |
| SCHEMBL7471305 | 0.84 | LMNA (0.54) | LMNAALDH1A1TSHRESR1CHRM1 | |
| SCHEMBL27428199 | 0.84 | LMNA (0.57) | LMNAALDH1A1TSHRESR1CHRM1 | |
| SCHEMBL7471658 | 0.84 | LOXL2 (0.62) | ALDH1A1CYP4F2CYP4A11KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859774-B1 | SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES | BAYER AG (DE) | 2002-04-03 | — | — | EP | disclosed |