Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457921 | 0.86 | MEN1 (0.62) | ALDH1A1HPGDMEN1KMT2ATDP1 | |
| SCHEMBL7460357 | 0.84 | L3MBTL1 (0.49) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL17622904 | 0.82 | ALDH1A1 (0.59) | ALDH1A1HPGDMEN1KMT2ATDP1 | |
| SCHEMBL16264706 | 0.82 | MEN1 (0.80) | ALDH1A1HPGDMEN1KMT2ATDP1 | |
| SCHEMBL17622466 | 0.80 | KMT2A (0.80) | ALDH1A1HPGDMEN1KMT2ATDP1 | |
| SCHEMBL17622900 | 0.79 | ALDH1A1 (0.66) | ALDH1A1HPGDMEN1KMT2ATDP1 | |
| SCHEMBL17622776 | 0.79 | TP53 (0.72) | ALDH1A1HPGDMEN1KMT2ATDP1 | |
| SCHEMBL1514827 | 0.79 | TDP1 (0.64) | ALDH1A1HPGDMEN1KMT2ATDP1 | |
| SCHEMBL17622775 | 0.78 | TDP1 (0.67) | ALDH1A1HPGDMEN1KMT2ATDP1 | |
| SCHEMBL17622902 | 0.78 | MEN1 (0.64) | ALDH1A1HPGDMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869122-B1 | Quinolinic sulfide derivatives acting as NMDA receptor antagonists and process for preparation thereof | KOREA RES INST CHEM TECH (KR) | 2002-12-04 | — | — | EP | disclosed |
| US-5990126-A | 4-HYDROXY-QUINOLIN-2-ONE DERIVATIVES SUBSTITUTED AT POSITION 3 WITH A SUBSTITUTED AROMATIC- OR HETEROAROMATIC-SULFIDE GROUP; ANTAGONIST OF EXCITATORY AMINO ACID FOR NMDA RECEPTORS; TREATING EPILEPSY, STROKE, PARKINSON'S DISEASE | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1999-11-23 | — | — | US | disclosed |
| EP-0869122-A1 | Quinolinic sulfide derivatives acting as NMDA receptor antagonists and process for preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-10-07 | — | — | EP | disclosed |