Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 3/20 | 0.31 |
| ▸ | CES1 | P23141 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474529 | 0.81 | DGAT1 (0.33) | CES2CES1CA1CA2CA4 | |
| SCHEMBL30882180 | 0.78 | CES2 (0.50) | ALDH1A1RECQLCES2CES1CA1 | |
| SCHEMBL7466460 | 0.78 | CES2 (0.50) | ALDH1A1CES2CES1CYP2C19 | |
| SCHEMBL7478644 | 0.78 | CES2 (0.50) | ALDH1A1RECQLCES2CES1CA1 | |
| SCHEMBL6902621 | 0.77 | SRC (0.36) | PTGS1PTGS2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5085546 | 0.76 | CES2 (0.39) | PTGS1PTGS2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL29009873 | 0.76 | SLC1A3 (0.38) | PTGS1PTGS2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5085545 | 0.76 | CES2 (0.39) | PTGS1PTGS2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL29653910 | 0.76 | CES2 (0.39) | PTGS1PTGS2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3735712 | 0.75 | PTGS1 (0.33) | PTGS1PTGS2CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077701-A4 | ANTI-VIRAL COMPOUNDS | LILLY CO ELI (US) | 2002-03-20 | — | — | EP | disclosed |
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |
| EP-1077701-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059587-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |